Add new database to Replication while running mysql (no replies)

Dear All,

I am using MySQL 5.1.54(64bit) and circular replication has been implemented. Now I have created a new database on master server and want to add then new database to replication do list just like we do in my.cnf file as replicate-do-db=DbName which needs MySQL restart to take effect. I want to know if this command can be given while mysql running and no need to restart using 'SET GLOBAL...' command?

Thanks for your support.